BDBM50205824 CHEMBL3913597

SMILES: CN1CCc2cccc(c2)[C@@H](Nc2ccc3c(N)nccc3c2)C(=O)N(C)Cc2cc(NC1=O)ccc2S(=O)(=O)C1CC1

InChI Key: InChIKey=JEVMWEZEXRXPSP-GDLZYMKVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor III/Factor VIIa (fVIIa) (Homo sapiens (Human))	BDBM50205824 (CHEMBL3913597) Show SMILES CN1CCc2cccc(c2)[C@@H](Nc2ccc3c(N)nccc3c2)C(=O)N(C)Cc2cc(NC1=O)ccc2S(=O)(=O)C1CC1 |r| Show InChI InChI=1S/C32H34N6O4S/c1-37-15-13-20-4-3-5-22(16-20)29(35-24-6-10-27-21(17-24)12-14-34-30(27)33)31(39)38(2)19-23-18-25(36-32(37)40)7-11-28(23)43(41,42)26-8-9-26/h3-7,10-12,14,16-18,26,29,35H,8-9,13,15,19H2,1-2H3,(H2,33,34)(H,36,40)/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human factor-7a/TF using S2288 as substrate measured after 60 mins at 37 degC				ACS Med Chem Lett 8: 67-72 (2017) Article DOI: 10.1021/acsmedchemlett.6b00375 BindingDB Entry DOI: 10.7270/Q20P120Q
					More data for this Ligand-Target Pair