BDBM50205837 CHEMBL3933476

SMILES: CN1Cc2cc(NC(=O)CCc3cccc(c3)[C@@H](Nc3ccc4c(N)ncc(F)c4c3)C1=O)ccc2S(=O)(=O)C1CC1

InChI Key: InChIKey=IEUVVPGYBKEWGD-GDLZYMKVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205837   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor III/Factor VIIa (fVIIa) (Homo sapiens (Human))	BDBM50205837 (CHEMBL3933476) Show SMILES CN1Cc2cc(NC(=O)CCc3cccc(c3)[C@@H](Nc3ccc4c(N)ncc(F)c4c3)C1=O)ccc2S(=O)(=O)C1CC1 |r| Show InChI InChI=1S/C31H30FN5O4S/c1-37-17-20-14-21(7-11-27(20)42(40,41)23-8-9-23)35-28(38)12-5-18-3-2-4-19(13-18)29(31(37)39)36-22-6-10-24-25(15-22)26(32)16-34-30(24)33/h2-4,6-7,10-11,13-16,23,29,36H,5,8-9,12,17H2,1H3,(H2,33,34)(H,35,38)/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human factor-7a/TF using S2288 as substrate measured after 60 mins at 37 degC				ACS Med Chem Lett 8: 67-72 (2017) Article DOI: 10.1021/acsmedchemlett.6b00375 BindingDB Entry DOI: 10.7270/Q20P120Q
					More data for this Ligand-Target Pair