BDBM50205944 CHEMBL436535::N-[(4-fluorophenyl)methyl]-1-[2-(1H-imidazol-1-yl)pyrimidin-4-yl]-2-piperidineacetamide

SMILES: Fc1ccc(CNC(=O)CC2CCCCN2c2ccnc(n2)-n2ccnc2)cc1

InChI Key: InChIKey=PFQCCCKWAOJRHG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50205944 (CHEMBL436535 | N-[(4-fluorophenyl)methyl]-1-[2-(1H...) Show SMILES Fc1ccc(CNC(=O)CC2CCCCN2c2ccnc(n2)-n2ccnc2)cc1 Show InChI InChI=1S/C21H23FN6O/c22-17-6-4-16(5-7-17)14-25-20(29)13-18-3-1-2-11-28(18)19-8-9-24-21(26-19)27-12-10-23-15-27/h4-10,12,15,18H,1-3,11,13-14H2,(H,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences Curated by ChEMBL					Assay Description Inhibition of cytokine-induced iNOS expressed in human A172 cells assessed as inhibition of NO formation				J Med Chem 50: 1146-57 (2007) Article DOI: 10.1021/jm061319i BindingDB Entry DOI: 10.7270/Q2SX6CWJ
					More data for this Ligand-Target Pair