BDBM50206197 CHEMBL235565::methyl 2-(2-(4-formylphenoxy)acetamido)-3-(1H-indol-3-yl)propanoate

SMILES: COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)COc1ccc(C=O)cc1

InChI Key: InChIKey=RUDNBTRMIBMJNB-UHFFFAOYSA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50206197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50206197 (CHEMBL235565 | methyl 2-(2-(4-formylphenoxy)acetam...) Show SMILES COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)COc1ccc(C=O)cc1 |w:4.4| Show InChI InChI=1S/C21H20N2O5/c1-27-21(26)19(10-15-11-22-18-5-3-2-4-17(15)18)23-20(25)13-28-16-8-6-14(12-24)7-9-16/h2-9,11-12,19,22H,10,13H2,1H3,(H,23,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-Sen University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as oxidation of L-DOPA by Lineweaver-Burke plot analysis				Eur J Med Chem 45: 639-46 (2010) Article DOI: 10.1016/j.ejmech.2009.11.007 BindingDB Entry DOI: 10.7270/Q2348M9F
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50206197 (CHEMBL235565 | methyl 2-(2-(4-formylphenoxy)acetam...) Show SMILES COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)COc1ccc(C=O)cc1 |w:4.4| Show InChI InChI=1S/C21H20N2O5/c1-27-21(26)19(10-15-11-22-18-5-3-2-4-17(15)18)23-20(25)13-28-16-8-6-14(12-24)7-9-16/h2-9,11-12,19,22H,10,13H2,1H3,(H,23,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-Sen University Curated by ChEMBL					Assay Description Inhibition of mashroom tyrosinase assessed as oxidation of L-DOPA by spectrophotometry				Eur J Med Chem 45: 639-46 (2010) Article DOI: 10.1016/j.ejmech.2009.11.007 BindingDB Entry DOI: 10.7270/Q2348M9F
					More data for this Ligand-Target Pair
Butyrylcholinesterase (BChE) (Equus caballus (Horse))	BDBM50206197 (CHEMBL235565 | methyl 2-(2-(4-formylphenoxy)acetam...) Show SMILES COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)COc1ccc(C=O)cc1 |w:4.4| Show InChI InChI=1S/C21H20N2O5/c1-27-21(26)19(10-15-11-22-18-5-3-2-4-17(15)18)23-20(25)13-28-16-8-6-14(12-24)7-9-16/h2-9,11-12,19,22H,10,13H2,1H3,(H,23,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of BuChE in horse serum				Bioorg Med Chem Lett 17: 2123-5 (2007) Article DOI: 10.1016/j.bmcl.2007.01.091 BindingDB Entry DOI: 10.7270/Q2RX9BQQ
					More data for this Ligand-Target Pair
Acetylcholinesterase (Tetronarce californica (Pacific electric ray) (Tor...)	BDBM50206197 (CHEMBL235565 | methyl 2-(2-(4-formylphenoxy)acetam...) Show SMILES COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)COc1ccc(C=O)cc1 |w:4.4| Show InChI InChI=1S/C21H20N2O5/c1-27-21(26)19(10-15-11-22-18-5-3-2-4-17(15)18)23-20(25)13-28-16-8-6-14(12-24)7-9-16/h2-9,11-12,19,22H,10,13H2,1H3,(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of AChE				Bioorg Med Chem Lett 17: 2123-5 (2007) Article DOI: 10.1016/j.bmcl.2007.01.091 BindingDB Entry DOI: 10.7270/Q2RX9BQQ
					More data for this Ligand-Target Pair