null

SMILES: C[C@](O)(c1cncc(c1)N1CCC2(CCOC2)CC1)C(F)(F)F

InChI Key: InChIKey=YLZOPOQTQWNNIZ-AWEZNQCLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50206214 (CHEMBL3973937) Show SMILES C[C@](O)(c1cncc(c1)N1CCC2(CCOC2)CC1)C(F)(F)F |r| Show InChI InChI=1S/C16H21F3N2O2/c1-14(22,16(17,18)19)12-8-13(10-20-9-12)21-5-2-15(3-6-21)4-7-23-11-15/h8-10,22H,2-7,11H2,1H3/t14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human CYP11B2-CLE9 expressed in chinese hamster V79 cells using 11-deoxycorticosterone as substrate preincubated for 1 hr followed by s...				ACS Med Chem Lett 8: 128-132 (2017) Article DOI: 10.1021/acsmedchemlett.6b00455 BindingDB Entry DOI: 10.7270/Q2BZ682V
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50206214 (CHEMBL3973937) Show SMILES C[C@](O)(c1cncc(c1)N1CCC2(CCOC2)CC1)C(F)(F)F |r| Show InChI InChI=1S/C16H21F3N2O2/c1-14(22,16(17,18)19)12-8-13(10-20-9-12)21-5-2-15(3-6-21)4-7-23-11-15/h8-10,22H,2-7,11H2,1H3/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	355	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human CYP11B1-8C7 expressed in chinese hamster V79 cells using 11-deoxycortisol as substrate preincubated for 1 hr followed by substrat...				ACS Med Chem Lett 8: 128-132 (2017) Article DOI: 10.1021/acsmedchemlett.6b00455 BindingDB Entry DOI: 10.7270/Q2BZ682V
					More data for this Ligand-Target Pair