BDBM50206445 CHEMBL3972822

SMILES: CCOC(=O)\C=C\C(=O)Nc1cccc(c1)-c1n[nH]c2ccccc12

InChI Key: InChIKey=DQZZMLOOOMDDOU-ZHACJKMWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206445   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50206445 (CHEMBL3972822) Show SMILES CCOC(=O)\C=C\C(=O)Nc1cccc(c1)-c1n[nH]c2ccccc12 Show InChI InChI=1S/C19H17N3O3/c1-2-25-18(24)11-10-17(23)20-14-7-5-6-13(12-14)19-15-8-3-4-9-16(15)21-22-19/h3-12H,2H2,1H3,(H,20,23)(H,21,22)/b11-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Taiwan National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...				Eur J Med Chem 124: 186-199 (2016) Article DOI: 10.1016/j.ejmech.2016.08.026 BindingDB Entry DOI: 10.7270/Q2668G5M
					More data for this Ligand-Target Pair