BDBM50206662 (S)-3-(6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)-N-methyl-N-((S)-1-((tetrahydro-2H-pyran-4-yl)methyl)pyrrolidin-3-yl)pyrrolidine-1-carboxamide::CHEMBL396957

SMILES: CN([C@H]1CCN(CC2CCOCC2)C1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=LJLZPSQRAPUBTC-GOTSBHOMSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50206662 ((S)-3-(6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimi...) Show SMILES CN([C@H]1CCN(CC2CCOCC2)C1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C28H34ClN5O3S/c1-31(22-6-10-32(16-22)15-19-8-12-37-13-9-19)28(36)33-11-7-23(17-33)34-18-30-24-14-25(38-26(24)27(34)35)20-2-4-21(29)5-3-20/h2-5,14,18-19,22-23H,6-13,15-17H2,1H3/t22-,23-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Binding affinity to human MCHR1				Bioorg Med Chem Lett 17: 2535-9 (2007) Article DOI: 10.1016/j.bmcl.2007.02.012 BindingDB Entry DOI: 10.7270/Q23778CV
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50206662 ((S)-3-(6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimi...) Show SMILES CN([C@H]1CCN(CC2CCOCC2)C1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C28H34ClN5O3S/c1-31(22-6-10-32(16-22)15-19-8-12-37-13-9-19)28(36)33-11-7-23(17-33)34-18-30-24-14-25(38-26(24)27(34)35)20-2-4-21(29)5-3-20/h2-5,14,18-19,22-23H,6-13,15-17H2,1H3/t22-,23-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 17: 2535-9 (2007) Article DOI: 10.1016/j.bmcl.2007.02.012 BindingDB Entry DOI: 10.7270/Q23778CV
					More data for this Ligand-Target Pair