BDBM50206672 (S)-3-(6-(4-methoxy-2-methylphenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)-N-methyl-N-((S)-1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-yl)pyrrolidine-1-carboxamide::CHEMBL232834

SMILES: COc1ccc(-c2cc3ncn([C@H]4CCN(C4)C(=O)N(C)[C@H]4CCN(C4)C4CCOCC4)c(=O)c3s2)c(C)c1

InChI Key: InChIKey=FUWGDNMCGSLMJS-VXKWHMMOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50206672 ((S)-3-(6-(4-methoxy-2-methylphenyl)-4-oxothieno[3,...) Show SMILES COc1ccc(-c2cc3ncn([C@H]4CCN(C4)C(=O)N(C)[C@H]4CCN(C4)C4CCOCC4)c(=O)c3s2)c(C)c1 Show InChI InChI=1S/C29H37N5O4S/c1-19-14-23(37-3)4-5-24(19)26-15-25-27(39-26)28(35)34(18-30-25)22-7-11-33(17-22)29(36)31(2)21-6-10-32(16-21)20-8-12-38-13-9-20/h4-5,14-15,18,20-22H,6-13,16-17H2,1-3H3/t21-,22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Binding affinity to human MCHR1				Bioorg Med Chem Lett 17: 2535-9 (2007) Article DOI: 10.1016/j.bmcl.2007.02.012 BindingDB Entry DOI: 10.7270/Q23778CV
					More data for this Ligand-Target Pair