BDBM50206676 (S)-3-(6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)-N-((S)-1-(3,3-dimethyl-2-oxobutyl)pyrrolidin-3-yl)-N-methylpyrrolidine-1-carboxamide::CHEMBL233027

SMILES: CN([C@H]1CCN(CC(=O)C(C)(C)C)C1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=GMHQJBKYAGURAB-SFTDATJTSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50206676 ((S)-3-(6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimi...) Show SMILES CN([C@H]1CCN(CC(=O)C(C)(C)C)C1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C28H34ClN5O3S/c1-28(2,3)24(35)16-32-11-9-20(14-32)31(4)27(37)33-12-10-21(15-33)34-17-30-22-13-23(38-25(22)26(34)36)18-5-7-19(29)8-6-18/h5-8,13,17,20-21H,9-12,14-16H2,1-4H3/t20-,21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Binding affinity to human MCHR1				Bioorg Med Chem Lett 17: 2535-9 (2007) Article DOI: 10.1016/j.bmcl.2007.02.012 BindingDB Entry DOI: 10.7270/Q23778CV
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50206676 ((S)-3-(6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimi...) Show SMILES CN([C@H]1CCN(CC(=O)C(C)(C)C)C1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C28H34ClN5O3S/c1-28(2,3)24(35)16-32-11-9-20(14-32)31(4)27(37)33-12-10-21(15-33)34-17-30-22-13-23(38-25(22)26(34)36)18-5-7-19(29)8-6-18/h5-8,13,17,20-21H,9-12,14-16H2,1-4H3/t20-,21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 17: 2535-9 (2007) Article DOI: 10.1016/j.bmcl.2007.02.012 BindingDB Entry DOI: 10.7270/Q23778CV
					More data for this Ligand-Target Pair