BDBM50206685 (S)-N-methyl-3-(4-oxo-6-(4-(trifluoromethoxy)phenyl)thieno[3,2-d]pyrimidin-3(4H)-yl)-N-((S)-1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-yl)pyrrolidine-1-carboxamide::CHEMBL234920

SMILES: CN([C@H]1CCN(C1)C1CCOCC1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=CFOQOXJLTXXJTH-SFTDATJTSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50206685 ((S)-N-methyl-3-(4-oxo-6-(4-(trifluoromethoxy)pheny...) Show SMILES CN([C@H]1CCN(C1)C1CCOCC1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C28H32F3N5O4S/c1-33(20-6-10-34(15-20)19-8-12-39-13-9-19)27(38)35-11-7-21(16-35)36-17-32-23-14-24(41-25(23)26(36)37)18-2-4-22(5-3-18)40-28(29,30)31/h2-5,14,17,19-21H,6-13,15-16H2,1H3/t20-,21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Binding affinity to human MCHR1				Bioorg Med Chem Lett 17: 2535-9 (2007) Article DOI: 10.1016/j.bmcl.2007.02.012 BindingDB Entry DOI: 10.7270/Q23778CV
					More data for this Ligand-Target Pair