BDBM50206690 (S)-3-(6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)-N-methyl-N-((S)-1-((tetrahydrofuran-3-yl)methyl)pyrrolidin-3-yl)pyrrolidine-1-carboxamide::CHEMBL232209

SMILES: CN([C@H]1CCN(CC2CCOC2)C1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=RZPQRBOXKISZBA-VRJTXETASA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206690   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50206690 ((S)-3-(6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimi...) Show SMILES CN([C@H]1CCN(CC2CCOC2)C1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 |w:7.6| Show InChI InChI=1S/C27H32ClN5O3S/c1-30(21-6-9-31(14-21)13-18-8-11-36-16-18)27(35)32-10-7-22(15-32)33-17-29-23-12-24(37-25(23)26(33)34)19-2-4-20(28)5-3-19/h2-5,12,17-18,21-22H,6-11,13-16H2,1H3/t18?,21-,22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Binding affinity to human MCHR1				Bioorg Med Chem Lett 17: 2535-9 (2007) Article DOI: 10.1016/j.bmcl.2007.02.012 BindingDB Entry DOI: 10.7270/Q23778CV
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50206690 ((S)-3-(6-(4-chlorophenyl)-4-oxothieno[3,2-d]pyrimi...) Show SMILES CN([C@H]1CCN(CC2CCOC2)C1)C(=O)N1CC[C@@H](C1)n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1 |w:7.6| Show InChI InChI=1S/C27H32ClN5O3S/c1-30(21-6-9-31(14-21)13-18-8-11-36-16-18)27(35)32-10-7-22(15-32)33-17-29-23-12-24(37-25(23)26(33)34)19-2-4-20(28)5-3-19/h2-5,12,17-18,21-22H,6-11,13-16H2,1H3/t18?,21-,22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 17: 2535-9 (2007) Article DOI: 10.1016/j.bmcl.2007.02.012 BindingDB Entry DOI: 10.7270/Q23778CV
					More data for this Ligand-Target Pair