BindingDB logo
myBDB logout

null

SMILES: COc1ccc(F)c(CC2CCN(CC2)C2CCN(CC2)c2ccc(OC)c(OC)c2)c1

InChI Key: InChIKey=WYCCDFKHRWDHTD-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206789   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Homo sapiens (Human))		BDBM50206789
PNG
(CHEMBL3981001)
Show SMILES COc1ccc(F)c(CC2CCN(CC2)C2CCN(CC2)c2ccc(OC)c(OC)c2)c1
Show InChI InChI=1S/C26H35FN2O3/c1-30-23-5-6-24(27)20(17-23)16-19-8-12-28(13-9-19)21-10-14-29(15-11-21)22-4-7-25(31-2)26(18-22)32-3/h4-7,17-19,21H,8-16H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
<100n/an/an/an/an/an/an/an/a



Sumitomo Dainippon Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranes after 1 hr by liquid scintillation counting method

Bioorg Med Chem 25: 293-304 (2017)


Article DOI: 10.1016/j.bmc.2016.10.034
BindingDB Entry DOI: 10.7270/Q2571F0B
More data for this
Ligand-Target Pair