BindingDB PrimarySearch

BDBM50206821 (R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-trifluorophenyl)butan-1-one hydrochloride::CHEMBL535180

SMILES: N[C@@H](CC(=O)N1CCCCN1C(=O)c1ccccc1)Cc1cc(F)c(F)cc1F

InChI Key: InChIKey=NBEBUKKRRLTYFD-MRXNPFEDSA-N

Data: 1 KI 8 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50206821
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dipeptidyl peptidase IV (Sus scrofa (pig))	BDBM50206821 ((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of pig kidney DPP4				Bioorg Med Chem Lett 17: 2622-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.111 BindingDB Entry DOI: 10.7270/Q21V5FS4
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50206821 ((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of POP				Bioorg Med Chem Lett 17: 2622-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.111 BindingDB Entry DOI: 10.7270/Q21V5FS4
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50206821 ((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of APN				Bioorg Med Chem Lett 17: 2622-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.111 BindingDB Entry DOI: 10.7270/Q21V5FS4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50206821 ((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DPP9				Bioorg Med Chem Lett 17: 3716-21 (2007) Article DOI: 10.1016/j.bmcl.2007.04.031 BindingDB Entry DOI: 10.7270/Q2D21ZTR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50206821 ((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DPP2				Bioorg Med Chem Lett 17: 2622-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.111 BindingDB Entry DOI: 10.7270/Q21V5FS4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50206821 ((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem Lett 17: 2622-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.111 BindingDB Entry DOI: 10.7270/Q21V5FS4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50206821 ((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DPP8				Bioorg Med Chem Lett 17: 3716-21 (2007) Article DOI: 10.1016/j.bmcl.2007.04.031 BindingDB Entry DOI: 10.7270/Q2D21ZTR
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50206821 ((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DPP8				Bioorg Med Chem Lett 17: 2622-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.111 BindingDB Entry DOI: 10.7270/Q21V5FS4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50206821 ((R)-3-amino-1-(2-benzoylpiperazin-1-yl)-4-(2,4,5-t...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DPP9				Bioorg Med Chem Lett 17: 2622-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.111 BindingDB Entry DOI: 10.7270/Q21V5FS4
					More data for this Ligand-Target Pair