BDBM50206912 (+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol-3-yl)phenyl]-1-O-(4-phenylbutyl)-2-Otetradecylglycerol::CHEMBL353623

SMILES: CCCCCCCCCCCCCCOC(COCCCCc1ccccc1)COc1ccc(cc1)-c1nc(=O)o[nH]1

InChI Key: InChIKey=ABMZPRJSVFWQHA-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2 group V (Homo sapiens (Human))	BDBM50206912 ((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...) Show SMILES CCCCCCCCCCCCCCOC(COCCCCc1ccccc1)COc1ccc(cc1)-c1nc(=O)o[nH]1 Show InChI InChI=1S/C35H52N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-17-27-40-33(28-39-26-18-16-21-30-19-14-13-15-20-30)29-41-32-24-22-31(23-25-32)34-36-35(38)42-37-34/h13-15,19-20,22-25,33H,2-12,16-18,21,26-29H2,1H3,(H,36,37,38)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris7-Denis Diderot Curated by ChEMBL					Assay Description Inhibition of human group V PLA2 in [3H]oleate-labeled Escherichia coli membrane by radiometric assay				J Med Chem 50: 1618-26 (2007) Article DOI: 10.1021/jm060082n BindingDB Entry DOI: 10.7270/Q2TQ6174
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50206912 ((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...) Show SMILES CCCCCCCCCCCCCCOC(COCCCCc1ccccc1)COc1ccc(cc1)-c1nc(=O)o[nH]1 Show InChI InChI=1S/C35H52N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-17-27-40-33(28-39-26-18-16-21-30-19-14-13-15-20-30)29-41-32-24-22-31(23-25-32)34-36-35(38)42-37-34/h13-15,19-20,22-25,33H,2-12,16-18,21,26-29H2,1H3,(H,36,37,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris7-Denis Diderot Curated by ChEMBL					Assay Description Inhibition of human group IIA PLA2 in [3H]oleate-labeled Escherichia coli membrane by radiometric assay				J Med Chem 50: 1618-26 (2007) Article DOI: 10.1021/jm060082n BindingDB Entry DOI: 10.7270/Q2TQ6174
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50206912 ((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...) Show SMILES CCCCCCCCCCCCCCOC(COCCCCc1ccccc1)COc1ccc(cc1)-c1nc(=O)o[nH]1 Show InChI InChI=1S/C35H52N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-17-27-40-33(28-39-26-18-16-21-30-19-14-13-15-20-30)29-41-32-24-22-31(23-25-32)34-36-35(38)42-37-34/h13-15,19-20,22-25,33H,2-12,16-18,21,26-29H2,1H3,(H,36,37,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris7-Denis Diderot Curated by ChEMBL					Assay Description Inhibition of human group IIA PLA2 by fluorimetric assay				J Med Chem 50: 1618-26 (2007) Article DOI: 10.1021/jm060082n BindingDB Entry DOI: 10.7270/Q2TQ6174
					More data for this Ligand-Target Pair
Phospholipase A2 (Homo sapiens (Human))	BDBM50206912 ((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...) Show SMILES CCCCCCCCCCCCCCOC(COCCCCc1ccccc1)COc1ccc(cc1)-c1nc(=O)o[nH]1 Show InChI InChI=1S/C35H52N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-17-27-40-33(28-39-26-18-16-21-30-19-14-13-15-20-30)29-41-32-24-22-31(23-25-32)34-36-35(38)42-37-34/h13-15,19-20,22-25,33H,2-12,16-18,21,26-29H2,1H3,(H,36,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris7-Denis Diderot Curated by ChEMBL					Assay Description Inhibition of human group IB PLA2 in [3H]oleate-labeled Escherichia coli membrane by radiometric assay				J Med Chem 50: 1618-26 (2007) Article DOI: 10.1021/jm060082n BindingDB Entry DOI: 10.7270/Q2TQ6174
					More data for this Ligand-Target Pair
Phospholipase A2, major isoenzyme (Sus scrofa (pig))	BDBM50206912 ((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...) Show SMILES CCCCCCCCCCCCCCOC(COCCCCc1ccccc1)COc1ccc(cc1)-c1nc(=O)o[nH]1 Show InChI InChI=1S/C35H52N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-17-27-40-33(28-39-26-18-16-21-30-19-14-13-15-20-30)29-41-32-24-22-31(23-25-32)34-36-35(38)42-37-34/h13-15,19-20,22-25,33H,2-12,16-18,21,26-29H2,1H3,(H,36,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris7-Denis Diderot Curated by ChEMBL					Assay Description Inhibition of pig group IB PLA2 by fluorimetric assay				J Med Chem 50: 1618-26 (2007) Article DOI: 10.1021/jm060082n BindingDB Entry DOI: 10.7270/Q2TQ6174
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50206912 ((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...) Show SMILES CCCCCCCCCCCCCCOC(COCCCCc1ccccc1)COc1ccc(cc1)-c1nc(=O)o[nH]1 Show InChI InChI=1S/C35H52N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-17-27-40-33(28-39-26-18-16-21-30-19-14-13-15-20-30)29-41-32-24-22-31(23-25-32)34-36-35(38)42-37-34/h13-15,19-20,22-25,33H,2-12,16-18,21,26-29H2,1H3,(H,36,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université Paris7-Denis Diderot Curated by ChEMBL					Assay Description Inhibition of human group X PLA2 in [3H]oleate-labeled Escherichia coli membrane by radiometric assay				J Med Chem 50: 1618-26 (2007) Article DOI: 10.1021/jm060082n BindingDB Entry DOI: 10.7270/Q2TQ6174
					More data for this Ligand-Target Pair