BDBM50206945 CHEMBL3909248

SMILES: [H][C@@]12CC[C@@](O)(C#C[Si](C)(C)C)[C@@]1(C)C[C@H](O)[C@]1([H])c3ccc(cc3CC[C@@]21[H])C(=O)Nc1cccnc1C

InChI Key: InChIKey=FLEOABKAHZYTNM-SXRKIBQPSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206945 (CHEMBL3909248) Show SMILES [H][C@@]12CC[C@@](O)(C#C[Si](C)(C)C)[C@@]1(C)C[C@H](O)[C@]1([H])c3ccc(cc3CC[C@@]21[H])C(=O)Nc1cccnc1C |r| Show InChI InChI=1S/C30H38N2O3Si/c1-19-25(7-6-15-31-19)32-28(34)21-9-10-22-20(17-21)8-11-23-24-12-13-30(35,14-16-36(3,4)5)29(24,2)18-26(33)27(22)23/h6-7,9-10,15,17,23-24,26-27,33,35H,8,11-13,18H2,1-5H3,(H,32,34)/t23-,24-,26-,27+,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Agonist activity at GR in human HepG2 cells assessed as protein mediated-transcriptional activity by MMTV-promoter driven luciferase reporter gene as...				Bioorg Med Chem Lett 27: 347-353 (2017) Article DOI: 10.1016/j.bmcl.2016.11.007 BindingDB Entry DOI: 10.7270/Q24B339Q
					More data for this Ligand-Target Pair