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SMILES: CC(C)Cn1c2nc(CC3CC4CCC3C4)[nH]c2c(=O)n(C)c1=O

InChI Key: InChIKey=CLZRCWCUPGPJDU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207137   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50207137
PNG
(8-(bicyclo[2.2.1]heptan-2-ylmethyl)-3-isobutyl-1-m...)
Show SMILES CC(C)Cn1c2nc(CC3CC4CCC3C4)[nH]c2c(=O)n(C)c1=O |THB:8:9:15:13.12|
Show InChI InChI=1S/C18H26N4O2/c1-10(2)9-22-16-15(17(23)21(3)18(22)24)19-14(20-16)8-13-7-11-4-5-12(13)6-11/h10-13H,4-9H2,1-3H3,(H,19,20)
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MMDB

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PubMed
n/an/a 25n/an/an/an/an/an/a



Novartis Institutes of Biomedical Research

Curated by ChEMBL


Assay Description
Inhibition of human platelet PDE5 by [3H]cGMP scintillation proximity assay

Bioorg Med Chem Lett 17: 2376-9 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.019
BindingDB Entry DOI: 10.7270/Q2X63NSC
More data for this
Ligand-Target Pair