BDBM50207379 CHEMBL3944368

SMILES: CN(C)c1ccc(NC(=O)C(=O)c2ccc3n(Cc4ccc(Cl)cc4)c4ccccc4c3c2)cc1

InChI Key: InChIKey=CWVWHJURBWGAKN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pancreatic lipase (Sus scrofa (Pig))	BDBM50207379 (CHEMBL3944368) Show SMILES CN(C)c1ccc(NC(=O)C(=O)c2ccc3n(Cc4ccc(Cl)cc4)c4ccccc4c3c2)cc1 Show InChI InChI=1S/C29H24ClN3O2/c1-32(2)23-14-12-22(13-15-23)31-29(35)28(34)20-9-16-27-25(17-20)24-5-3-4-6-26(24)33(27)18-19-7-10-21(30)11-8-19/h3-17H,18H2,1-2H3,(H,31,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology and Science Pilani (Pilani Campus) Curated by ChEMBL					Assay Description Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...				Bioorg Med Chem 25: 609-620 (2017) Article DOI: 10.1016/j.bmc.2016.11.031 BindingDB Entry DOI: 10.7270/Q2J968C6
					More data for this Ligand-Target Pair