BDBM50207381 CHEMBL3934940
SMILES: COc1cc(NC(=O)C(=O)c2ccc3n(Cc4ccc(Cl)cc4)c4ccccc4c3c2)cc(OC)c1OC
InChI Key: InChIKey=WPXMYQOILUKHRF-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pancreatic lipase (Sus scrofa (Pig)) | BDBM50207381 (CHEMBL3934940) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology and Science Pilani (Pilani Campus) Curated by ChEMBL | Assay Description Competitive inhibition of porcine pancreatic lipase 4-nitrophenyl butyrate substrate preincubated for 30 mins followed by substrate addition measured... | Bioorg Med Chem 25: 609-620 (2017) Article DOI: 10.1016/j.bmc.2016.11.031 BindingDB Entry DOI: 10.7270/Q2J968C6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Pancreatic triacylglycerol lipase (Sus scrofa (Pig)) | BDBM50207381 (CHEMBL3934940) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology and Science Pilani (Pilani Campus) Curated by ChEMBL | Assay Description Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi... | Bioorg Med Chem 25: 609-620 (2017) Article DOI: 10.1016/j.bmc.2016.11.031 BindingDB Entry DOI: 10.7270/Q2J968C6 | |||||||||||
More data for this Ligand-Target Pair |