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BDBM50207390 CHEMBL3976270

SMILES: CCn1c2ccccc2c2cc(ccc12)C(=O)C(=O)Nc1cc(OC)c(OC)c(OC)c1

InChI Key: InChIKey=VEWMAPJRGRNEGB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207390   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Pancreatic lipase


(Sus scrofa (Pig))		BDBM50207390
PNG
(CHEMBL3976270)
Show SMILES CCn1c2ccccc2c2cc(ccc12)C(=O)C(=O)Nc1cc(OC)c(OC)c(OC)c1
Show InChI InChI=1S/C25H24N2O5/c1-5-27-19-9-7-6-8-17(19)18-12-15(10-11-20(18)27)23(28)25(29)26-16-13-21(30-2)24(32-4)22(14-16)31-3/h6-14H,5H2,1-4H3,(H,26,29)
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Similars
Article
PubMed
n/an/a 1.14E+4n/an/an/an/an/an/a



Birla Institute of Technology and Science Pilani (Pilani Campus)

Curated by ChEMBL


Assay Description
Inhibition of porcine pancreatic lipase assessed as reduction in 4-nitrophenol formation from 4-nitrophenyl butyrate substrate preincubated for 30 mi...

Bioorg Med Chem 25: 609-620 (2017)


Article DOI: 10.1016/j.bmc.2016.11.031
BindingDB Entry DOI: 10.7270/Q2J968C6
More data for this
Ligand-Target Pair