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SMILES: Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cccc3n(C)ncc23)c1

InChI Key: InChIKey=YDQKGDYQOOLJNI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207479   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50207479
PNG
(CHEMBL222974 | N-[4-(1-methyl-1H-indazol-4-yl)-phe...)
Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cccc3n(C)ncc23)c1
Show InChI InChI=1S/C22H20N4O/c1-15-5-3-6-18(13-15)25-22(27)24-17-11-9-16(10-12-17)19-7-4-8-21-20(19)14-23-26(21)2/h3-14H,1-2H3,(H2,24,25,27)
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n/an/a 465n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISA

J Med Chem 50: 1584-97 (2007)


Article DOI: 10.1021/jm061280h
BindingDB Entry DOI: 10.7270/Q2DJ5F95
More data for this
Ligand-Target Pair