BDBM50207505 1-(4-(3-amino-7-(2-(diethylamino)ethoxy)-1H-indazol-4-yl)phenyl)-3-m-tolylurea::CHEMBL219774::N-{4-[3-amino-7-(2-diethylaminoethoxy)-1H-indazol-4-yl]-phenyl}-N'-(3-methylphenyl)urea

SMILES: CCN(CC)CCOc1ccc(-c2ccc(NC(=O)Nc3cccc(C)c3)cc2)c2c(N)n[nH]c12

InChI Key: InChIKey=ILTQFFVJLSZIER-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50207505   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50207505 (1-(4-(3-amino-7-(2-(diethylamino)ethoxy)-1H-indazo...) Show SMILES CCN(CC)CCOc1ccc(-c2ccc(NC(=O)Nc3cccc(C)c3)cc2)c2c(N)n[nH]c12 Show InChI InChI=1S/C27H32N6O2/c1-4-33(5-2)15-16-35-23-14-13-22(24-25(23)31-32-26(24)28)19-9-11-20(12-10-19)29-27(34)30-21-8-6-7-18(3)17-21/h6-14,17H,4-5,15-16H2,1-3H3,(H3,28,31,32)(H2,29,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of c-Kit by HTRF assay				J Med Chem 50: 1584-97 (2007) Article DOI: 10.1021/jm061280h BindingDB Entry DOI: 10.7270/Q2DJ5F95
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50207505 (1-(4-(3-amino-7-(2-(diethylamino)ethoxy)-1H-indazo...) Show SMILES CCN(CC)CCOc1ccc(-c2ccc(NC(=O)Nc3cccc(C)c3)cc2)c2c(N)n[nH]c12 Show InChI InChI=1S/C27H32N6O2/c1-4-33(5-2)15-16-35-23-14-13-22(24-25(23)31-32-26(24)28)19-9-11-20(12-10-19)29-27(34)30-21-8-6-7-18(3)17-21/h6-14,17H,4-5,15-16H2,1-3H3,(H3,28,31,32)(H2,29,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Punjabi University Curated by ChEMBL					Assay Description Inhibition of c-Kit by HTRF method				Eur J Med Chem 45: 393-404 (2010) Article DOI: 10.1016/j.ejmech.2009.09.013 BindingDB Entry DOI: 10.7270/Q2RX9C6D
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50207505 (1-(4-(3-amino-7-(2-(diethylamino)ethoxy)-1H-indazo...) Show SMILES CCN(CC)CCOc1ccc(-c2ccc(NC(=O)Nc3cccc(C)c3)cc2)c2c(N)n[nH]c12 Show InChI InChI=1S/C27H32N6O2/c1-4-33(5-2)15-16-35-23-14-13-22(24-25(23)31-32-26(24)28)19-9-11-20(12-10-19)29-27(34)30-21-8-6-7-18(3)17-21/h6-14,17H,4-5,15-16H2,1-3H3,(H3,28,31,32)(H2,29,30,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT3 by HTRF assay				J Med Chem 50: 1584-97 (2007) Article DOI: 10.1021/jm061280h BindingDB Entry DOI: 10.7270/Q2DJ5F95
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50207505 (1-(4-(3-amino-7-(2-(diethylamino)ethoxy)-1H-indazo...) Show SMILES CCN(CC)CCOc1ccc(-c2ccc(NC(=O)Nc3cccc(C)c3)cc2)c2c(N)n[nH]c12 Show InChI InChI=1S/C27H32N6O2/c1-4-33(5-2)15-16-35-23-14-13-22(24-25(23)31-32-26(24)28)19-9-11-20(12-10-19)29-27(34)30-21-8-6-7-18(3)17-21/h6-14,17H,4-5,15-16H2,1-3H3,(H3,28,31,32)(H2,29,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISA				J Med Chem 50: 1584-97 (2007) Article DOI: 10.1021/jm061280h BindingDB Entry DOI: 10.7270/Q2DJ5F95
					More data for this Ligand-Target Pair