BDBM50207512 CHEMBL375284::N-[4-(1H-indazol-4-yl)-phenyl]-N'-(3-methylphenyl)urea

SMILES: Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]ncc23)c1

InChI Key: InChIKey=PJSBFZAYJQMORO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50207512 (CHEMBL375284 | N-[4-(1H-indazol-4-yl)-phenyl]-N'-(...) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]ncc23)c1 Show InChI InChI=1S/C21H18N4O/c1-14-4-2-5-17(12-14)24-21(26)23-16-10-8-15(9-11-16)18-6-3-7-20-19(18)13-22-25-20/h2-13H,1H3,(H,22,25)(H2,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation in mouse 3T3 cells by ELISA				J Med Chem 50: 1584-97 (2007) Article DOI: 10.1021/jm061280h BindingDB Entry DOI: 10.7270/Q2DJ5F95
					More data for this Ligand-Target Pair