BDBM50207540 CHEMBL3896854

SMILES: Fc1ccc(cc1)C(=O)Nc1ccccc1C(=O)Nc1ccc2c(cc(=O)oc2c1)C(F)(F)F

InChI Key: InChIKey=QSDYUKWZTCFDHL-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50207540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase (Homo sapiens (Human))	BDBM50207540 (CHEMBL3896854) Show SMILES Fc1ccc(cc1)C(=O)Nc1ccccc1C(=O)Nc1ccc2c(cc(=O)oc2c1)C(F)(F)F Show InChI InChI=1S/C24H14F4N2O4/c25-14-7-5-13(6-8-14)22(32)30-19-4-2-1-3-17(19)23(33)29-15-9-10-16-18(24(26,27)28)12-21(31)34-20(16)11-15/h1-12H,(H,29,33)(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase-12 preincubated for 6 hrs by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 677-683 (2017) Article DOI: 10.1016/j.bmc.2016.11.039 BindingDB Entry DOI: 10.7270/Q2N29ZZR
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50207540 (CHEMBL3896854) Show SMILES Fc1ccc(cc1)C(=O)Nc1ccccc1C(=O)Nc1ccc2c(cc(=O)oc2c1)C(F)(F)F Show InChI InChI=1S/C24H14F4N2O4/c25-14-7-5-13(6-8-14)22(32)30-19-4-2-1-3-17(19)23(33)29-15-9-10-16-18(24(26,27)28)12-21(31)34-20(16)11-15/h1-12H,(H,29,33)(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase-9 preincubated for 6 hrs by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 677-683 (2017) Article DOI: 10.1016/j.bmc.2016.11.039 BindingDB Entry DOI: 10.7270/Q2N29ZZR
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50207540 (CHEMBL3896854) Show SMILES Fc1ccc(cc1)C(=O)Nc1ccccc1C(=O)Nc1ccc2c(cc(=O)oc2c1)C(F)(F)F Show InChI InChI=1S/C24H14F4N2O4/c25-14-7-5-13(6-8-14)22(32)30-19-4-2-1-3-17(19)23(33)29-15-9-10-16-18(24(26,27)28)12-21(31)34-20(16)11-15/h1-12H,(H,29,33)(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase-1 preincubated for 6 hrs by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 677-683 (2017) Article DOI: 10.1016/j.bmc.2016.11.039 BindingDB Entry DOI: 10.7270/Q2N29ZZR
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50207540 (CHEMBL3896854) Show SMILES Fc1ccc(cc1)C(=O)Nc1ccccc1C(=O)Nc1ccc2c(cc(=O)oc2c1)C(F)(F)F Show InChI InChI=1S/C24H14F4N2O4/c25-14-7-5-13(6-8-14)22(32)30-19-4-2-1-3-17(19)23(33)29-15-9-10-16-18(24(26,27)28)12-21(31)34-20(16)11-15/h1-12H,(H,29,33)(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase-2 preincubated for 6 hrs by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 677-683 (2017) Article DOI: 10.1016/j.bmc.2016.11.039 BindingDB Entry DOI: 10.7270/Q2N29ZZR
					More data for this Ligand-Target Pair