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BDBM50207583 CHEMBL234279::N-[2-(5-nitro-1H-benzoimidazol-2-yl)-benzoyl]-guanidine

SMILES: NC(=N)NC(=O)c1ccccc1-c1nc2ccc(cc2[nH]1)[N+]([O-])=O

InChI Key: InChIKey=NRURZLYPRTWJRR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207583   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/hydrogen exchanger 1


(Rattus norvegicus)
BDBM50207583
PNG
(CHEMBL234279 | N-[2-(5-nitro-1H-benzoimidazol-2-yl...)
Show SMILES NC(=N)NC(=O)c1ccccc1-c1nc2ccc(cc2[nH]1)[N+]([O-])=O
Show InChI InChI=1S/C15H12N6O3/c16-15(17)20-14(22)10-4-2-1-3-9(10)13-18-11-6-5-8(21(23)24)7-12(11)19-13/h1-7H,(H,18,19)(H4,16,17,20,22)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.05n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of NHE1 in rat platelets by Platelet swelling assay


Bioorg Med Chem Lett 17: 2430-3 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.035
BindingDB Entry DOI: 10.7270/Q21C1WJ1
More data for this
Ligand-Target Pair