null
SMILES: CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cccc(c1)C(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O
InChI Key: InChIKey=LGORGTYVVSKEOB-KXJTVXFKSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50207826 (CHEMBL393867 | H-mCpa-ser-Gly-Phe-Leu-Thr-OH) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation Curated by ChEMBL | Assay Description Displacement of [3H]diprenorphine from human cloned delta opioid receptor | Bioorg Med Chem Lett 17: 2656-60 (2007) Article DOI: 10.1016/j.bmcl.2007.01.092 BindingDB Entry DOI: 10.7270/Q27S7NGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50207826 (CHEMBL393867 | H-mCpa-ser-Gly-Phe-Leu-Thr-OH) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation Curated by ChEMBL | Assay Description Displacement of [3H]diprenorphine from human cloned mu opioid receptor | Bioorg Med Chem Lett 17: 2656-60 (2007) Article DOI: 10.1016/j.bmcl.2007.01.092 BindingDB Entry DOI: 10.7270/Q27S7NGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50207826 (CHEMBL393867 | H-mCpa-ser-Gly-Phe-Leu-Thr-OH) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation Curated by ChEMBL | Assay Description Displacement of [3H]diprenorphine from human cloned kappa opioid receptor | Bioorg Med Chem Lett 17: 2656-60 (2007) Article DOI: 10.1016/j.bmcl.2007.01.092 BindingDB Entry DOI: 10.7270/Q27S7NGH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50207826 (CHEMBL393867 | H-mCpa-ser-Gly-Phe-Leu-Thr-OH) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 730 | n/a | n/a | n/a | n/a |
Adolor Corporation Curated by ChEMBL | Assay Description Agonist activity at human cloned delta opioid receptor assessed as stimulation of [35S]GTP-gamma-S binding | Bioorg Med Chem Lett 17: 2656-60 (2007) Article DOI: 10.1016/j.bmcl.2007.01.092 BindingDB Entry DOI: 10.7270/Q27S7NGH | |||||||||||
More data for this Ligand-Target Pair |