BDBM50207862 3-isopropyl-N-(3-(3-(2-(methylamino)pyridin-4-yl)pyridin-2-yloxy)phenyl)benzamide::CHEMBL246150
SMILES: CNc1cc(ccn1)-c1cccnc1Oc1cccc(NC(=O)c2cccc(c2)C(C)C)c1
InChI Key: InChIKey=FODDHYRWTNFLQO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50207862 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50207862
(3-isopropyl-N-(3-(3-(2-(methylamino)pyridin-4-yl)p...)Show SMILES CNc1cc(ccn1)-c1cccnc1Oc1cccc(NC(=O)c2cccc(c2)C(C)C)c1 Show InChI InChI=1S/C27H26N4O2/c1-18(2)19-7-4-8-21(15-19)26(32)31-22-9-5-10-23(17-22)33-27-24(11-6-13-30-27)20-12-14-29-25(16-20)28-3/h4-18H,1-3H3,(H,28,29)(H,31,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of KDR after 90 mins by HTRF assay |
Bioorg Med Chem Lett 17: 2886-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.02.067
BindingDB Entry DOI: 10.7270/Q2445M4C |
More data for this
Ligand-Target Pair | |
Angiopoietin-1 receptor
(Homo sapiens (Human)) | BDBM50207862
(3-isopropyl-N-(3-(3-(2-(methylamino)pyridin-4-yl)p...)Show SMILES CNc1cc(ccn1)-c1cccnc1Oc1cccc(NC(=O)c2cccc(c2)C(C)C)c1 Show InChI InChI=1S/C27H26N4O2/c1-18(2)19-7-4-8-21(15-19)26(32)31-22-9-5-10-23(17-22)33-27-24(11-6-13-30-27)20-12-14-29-25(16-20)28-3/h4-18H,1-3H3,(H,28,29)(H,31,32) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Tie2 after 90 mins by HTRF assay |
Bioorg Med Chem Lett 17: 2886-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.02.067
BindingDB Entry DOI: 10.7270/Q2445M4C |
More data for this
Ligand-Target Pair | |
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