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SMILES: Cc1ccccc1N1CCN(CC(O)COc2cccc(c2)C(=O)CCc2ccccc2)CC1

InChI Key: InChIKey=SQAMLCUZFXAOIV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50207980   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50207980
PNG
(1-(3-(2-hydroxy-3-(4-o-tolylpiperazin-1-yl)propoxy...)
Show SMILES Cc1ccccc1N1CCN(CC(O)COc2cccc(c2)C(=O)CCc2ccccc2)CC1
Show InChI InChI=1S/C29H34N2O3/c1-23-8-5-6-13-28(23)31-18-16-30(17-19-31)21-26(32)22-34-27-12-7-11-25(20-27)29(33)15-14-24-9-3-2-4-10-24/h2-13,20,26,32H,14-19,21-22H2,1H3
PDB

UniProtKB/SwissProt

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antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 74n/an/an/an/a



University of Vienna

Curated by ChEMBL


Assay Description
Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assay

J Med Chem 50: 1698-702 (2007)


Article DOI: 10.1021/jm060604z
BindingDB Entry DOI: 10.7270/Q2SB46JC
More data for this
Ligand-Target Pair