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BDBM50207997 3-(1-(3-methoxybenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one::CHEMBL225074

SMILES: COc1cccc(CN2CCC(CC2)N2CC(NC2=O)(c2ccccc2)c2ccccc2)c1

InChI Key: InChIKey=UUGHVUGONUOFJE-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207997   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50207997
PNG
(3-(1-(3-methoxybenzyl)-piperidin-4-yl)-5,5-dipheny...)
Show SMILES COc1cccc(CN2CCC(CC2)N2CC(NC2=O)(c2ccccc2)c2ccccc2)c1
Show InChI InChI=1S/C28H31N3O2/c1-33-26-14-8-9-22(19-26)20-30-17-15-25(16-18-30)31-21-28(29-27(31)32,23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-14,19,25H,15-18,20-21H2,1H3,(H,29,32)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
8.80n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHO K1 cells


J Med Chem 50: 1571-83 (2007)


Article DOI: 10.1021/jm061159a
BindingDB Entry DOI: 10.7270/Q2QV3M61
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50207997
PNG
(3-(1-(3-methoxybenzyl)-piperidin-4-yl)-5,5-dipheny...)
Show SMILES COc1cccc(CN2CCC(CC2)N2CC(NC2=O)(c2ccccc2)c2ccccc2)c1
Show InChI InChI=1S/C28H31N3O2/c1-33-26-14-8-9-22(19-26)20-30-17-15-25(16-18-30)31-21-28(29-27(31)32,23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-14,19,25H,15-18,20-21H2,1H3,(H,29,32)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
695n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHO K1 cells


J Med Chem 50: 1571-83 (2007)


Article DOI: 10.1021/jm061159a
BindingDB Entry DOI: 10.7270/Q2QV3M61
More data for this
Ligand-Target Pair