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BDBM50208041 1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-imidazolidin-1-yl]-1-(2-oxo-2-pyridin-2-ylethyl)-pyrrolidinium::CHEMBL222054

SMILES: C[N+]1(CC(=O)c2ccccn2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key: InChIKey=JMSDQUDVBLZSMZ-PXWGLLCJSA-O

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208041   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50208041
PNG
(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Show SMILES C[N+]1(CC(=O)c2ccccn2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C27H26F2N4O2/c1-33(17-25(34)24-4-2-3-14-30-24)15-13-23(16-33)32-18-27(31-26(32)35,19-5-9-21(28)10-6-19)20-7-11-22(29)12-8-20/h2-12,14,23H,13,15-18H2,1H3/p+1/t23-,33?/m1/s1
Reactome pathway
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Article
PubMed
2.61n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50208041
PNG
(1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...)
Show SMILES C[N+]1(CC(=O)c2ccccn2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C27H26F2N4O2/c1-33(17-25(34)24-4-2-3-14-30-24)15-13-23(16-33)32-18-27(31-26(32)35,19-5-9-21(28)10-6-19)20-7-11-22(29)12-8-20/h2-12,14,23H,13,15-18H2,1H3/p+1/t23-,33?/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
268n/an/an/an/an/an/an/an/a



Via Zambeletti 25

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methyl-scopalamine from human muscarinic M2 receptor expressed in CHOK1 cells


J Med Chem 50: 1693-7 (2007)


Article DOI: 10.1021/jm061160+
BindingDB Entry DOI: 10.7270/Q2M32VF5
More data for this
Ligand-Target Pair