BDBM50208120 5-(3-iodo-phenyl)-5-methyl-4-oxo-4,5-dihydro-furan-2-carboxylic acid::CHEMBL223013

SMILES: CC1(OC(=CC1=O)C(O)=O)c1cccc(I)c1

InChI Key: InChIKey=QJKQNKXFEZQYQP-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208120   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50208120 (5-(3-iodo-phenyl)-5-methyl-4-oxo-4,5-dihydro-furan...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1cccc(I)c1 |c:3| Show InChI InChI=1S/C12H9IO4/c1-12(7-3-2-4-8(13)5-7)10(14)6-9(17-12)11(15)16/h2-6H,1H3,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	430	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109a in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair
HM74 nicotinic acid GPCR (Homo sapiens (Human))	BDBM50208120 (5-(3-iodo-phenyl)-5-methyl-4-oxo-4,5-dihydro-furan...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1cccc(I)c1 |c:3| Show InChI InChI=1S/C12H9IO4/c1-12(7-3-2-4-8(13)5-7)10(14)6-9(17-12)11(15)16/h2-6H,1H3,(H,15,16)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair