BindingDB logo
myBDB logout

null

SMILES: CN(C)CCCNc1nc2ccccc2c2nc3ccccc3nc12

InChI Key: InChIKey=PNQMOYNEACMMAG-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50208197   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50208197
PNG
(CHEMBL3884560)
Show SMILES CN(C)CCCNc1nc2ccccc2c2nc3ccccc3nc12
Show InChI InChI=1S/C20H21N5/c1-25(2)13-7-12-21-20-19-18(14-8-3-4-9-15(14)24-20)22-16-10-5-6-11-17(16)23-19/h3-6,8-11H,7,12-13H2,1-2H3,(H,21,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.13E+4n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of human DNA topoisomerase 2alpha-mediated decatenation of kinetoplast DNA after 60 mins by agarose gel electrophoresis

Eur J Med Chem 123: 704-717 (2016)


Article DOI: 10.1016/j.ejmech.2016.07.063
BindingDB Entry DOI: 10.7270/Q2TQ63HJ
More data for this
Ligand-Target Pair