null

SMILES: [#6]-c1cc(-[#6])c(-[#8])c(c1)-[#6@@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-c1cc(-[#7])cc(c1)\[#7]=[#6]-1\[#7]-[#6]-[#6](F)-[#6]-[#7]-1

InChI Key: InChIKey=URDBOWYEVUVRDS-LJQANCHMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50209478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50209478 ((3R)-3-(2-(3-amino-5-(5-fluoro-1,4,5,6-tetrahydrop...) Show SMILES [#6]-c1cc(-[#6])c(-[#8])c(c1)-[#6@@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-c1cc(-[#7])cc(c1)\[#7]=[#6]-1\[#7]-[#6]-[#6](F)-[#6]-[#7]-1 Show InChI InChI=1S/C24H29FN6O5/c1-12-3-13(2)22(35)18(4-12)19(8-21(33)34)31-20(32)11-27-23(36)14-5-16(26)7-17(6-14)30-24-28-9-15(25)10-29-24/h3-7,15,19,35H,8-11,26H2,1-2H3,(H,27,36)(H,31,32)(H,33,34)(H2,28,29,30)/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of alphaVbeta6 integrin receptor in human HT29 cells				Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50209478 ((3R)-3-(2-(3-amino-5-(5-fluoro-1,4,5,6-tetrahydrop...) Show SMILES [#6]-c1cc(-[#6])c(-[#8])c(c1)-[#6@@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-c1cc(-[#7])cc(c1)\[#7]=[#6]-1\[#7]-[#6]-[#6](F)-[#6]-[#7]-1 Show InChI InChI=1S/C24H29FN6O5/c1-12-3-13(2)22(35)18(4-12)19(8-21(33)34)31-20(32)11-27-23(36)14-5-16(26)7-17(6-14)30-24-28-9-15(25)10-29-24/h3-7,15,19,35H,8-11,26H2,1-2H3,(H,27,36)(H,31,32)(H,33,34)(H2,28,29,30)/t19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells				Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4
					More data for this Ligand-Target Pair