BDBM50209493 3-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-6-[3-(2-methylphenyl)prop-2-enyl]-3,6-diazabicyclo[3.1.1]heptane fumarate

SMILES: Cc1ccccc1\C=C\CN1C2CC1CN(CCOC(c1ccc(F)cc1)c1ccc(F)cc1)C2

InChI Key: InChIKey=CDZLEERXDSZCII-QPJJXVBHSA-N

Data: 1 KI

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50209493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50209493 (3-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-6-[3-(2-m...) Show SMILES Cc1ccccc1\C=C\CN1C2CC1CN(CCOC(c1ccc(F)cc1)c1ccc(F)cc1)C2 |w:11.38,13.15,TLB:9:10:15.34.14:12,THB:16:15:10:12| Show InChI InChI=1S/C30H32F2N2O/c1-22-5-2-3-6-23(22)7-4-16-34-28-19-29(34)21-33(20-28)17-18-35-30(24-8-12-26(31)13-9-24)25-10-14-27(32)15-11-25/h2-15,28-30H,16-21H2,1H3/b7-4+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Sassari Curated by ChEMBL					Assay Description Inhibition of [3H]dopamine uptake at DAT in Sprague-Dawley rat striatum synaptosome				Bioorg Med Chem 15: 3748-55 (2007) Article DOI: 10.1016/j.bmc.2007.03.035 BindingDB Entry DOI: 10.7270/Q2M61M3F
					More data for this Ligand-Target Pair