BDBM50209524 (R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-5,6-difluoro-quinolin-4-ylamino]-propionic acid::CHEMBL396094

SMILES: CCOc1ccccc1-c1ccc(cc1)-c1nc2ccc(F)c(F)c2c(N[C@H](C)C(O)=O)c1C#N

InChI Key: InChIKey=PCLQBJLXAVFJEG-OAHLLOKOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50209524   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50209524 ((R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-5,6-dif...) Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2ccc(F)c(F)c2c(N[C@H](C)C(O)=O)c1C#N Show InChI InChI=1S/C27H21F2N3O3/c1-3-35-22-7-5-4-6-18(22)16-8-10-17(11-9-16)25-19(14-30)26(31-15(2)27(33)34)23-21(32-25)13-12-20(28)24(23)29/h4-13,15H,3H2,1-2H3,(H,31,32)(H,33,34)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE10A transfected in insect Sf9 cells by scintillation proximity assay				Bioorg Med Chem Lett 17: 2869-73 (2007) Article DOI: 10.1016/j.bmcl.2007.02.061 BindingDB Entry DOI: 10.7270/Q2NS0TK0
					More data for this Ligand-Target Pair