BDBM50209541 (R)-2-[6-chloro-3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-quinolin-4-ylamino]-propionic acid::CHEMBL439572

SMILES: CCOc1ccccc1-c1ccc(cc1)-c1nc2ccc(Cl)cc2c(N[C@H](C)C(O)=O)c1C#N

InChI Key: InChIKey=LIJDFVJSKFSHRR-MRXNPFEDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50209541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50209541 ((R)-2-[6-chloro-3-cyano-2-(2'-ethoxy-biphenyl-4-yl...) Show SMILES CCOc1ccccc1-c1ccc(cc1)-c1nc2ccc(Cl)cc2c(N[C@H](C)C(O)=O)c1C#N Show InChI InChI=1S/C27H22ClN3O3/c1-3-34-24-7-5-4-6-20(24)17-8-10-18(11-9-17)25-22(15-29)26(30-16(2)27(32)33)21-14-19(28)12-13-23(21)31-25/h4-14,16H,3H2,1-2H3,(H,30,31)(H,32,33)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE10A transfected in insect Sf9 cells by scintillation proximity assay				Bioorg Med Chem Lett 17: 2869-73 (2007) Article DOI: 10.1016/j.bmcl.2007.02.061 BindingDB Entry DOI: 10.7270/Q2NS0TK0
					More data for this Ligand-Target Pair