null

SMILES: Cc1ccsc1C1(O)CCN(CC1)C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=GGAITJRZAAULQE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50210241 (1-benzhydryl-4-(3-methylthiophen-2-yl)piperidin-4-...) Show SMILES Cc1ccsc1C1(O)CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25NOS/c1-18-12-17-26-22(18)23(25)13-15-24(16-14-23)21(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-12,17,21,25H,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210241 (1-benzhydryl-4-(3-methylthiophen-2-yl)piperidin-4-...) Show SMILES Cc1ccsc1C1(O)CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25NOS/c1-18-12-17-26-22(18)23(25)13-15-24(16-14-23)21(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-12,17,21,25H,13-16H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	756	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50210241 (1-benzhydryl-4-(3-methylthiophen-2-yl)piperidin-4-...) Show SMILES Cc1ccsc1C1(O)CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25NOS/c1-18-12-17-26-22(18)23(25)13-15-24(16-14-23)21(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-12,17,21,25H,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50210241 (1-benzhydryl-4-(3-methylthiophen-2-yl)piperidin-4-...) Show SMILES Cc1ccsc1C1(O)CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25NOS/c1-18-12-17-26-22(18)23(25)13-15-24(16-14-23)21(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-12,17,21,25H,13-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair