BDBM50210246 1-(bis(2-chlorophenyl)methyl)-4-(2-((methylamino)methyl)phenyl)piperidin-4-ol::CHEMBL232477

SMILES: CNCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl

InChI Key: InChIKey=CIUZZWVDZRCBDX-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50210246 (1-(bis(2-chlorophenyl)methyl)-4-(2-((methylamino)m...) Show SMILES CNCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl Show InChI InChI=1S/C26H28Cl2N2O/c1-29-18-19-8-2-5-11-22(19)26(31)14-16-30(17-15-26)25(20-9-3-6-12-23(20)27)21-10-4-7-13-24(21)28/h2-13,25,29,31H,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210246 (1-(bis(2-chlorophenyl)methyl)-4-(2-((methylamino)m...) Show SMILES CNCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl Show InChI InChI=1S/C26H28Cl2N2O/c1-29-18-19-8-2-5-11-22(19)26(31)14-16-30(17-15-26)25(20-9-3-6-12-23(20)27)21-10-4-7-13-24(21)28/h2-13,25,29,31H,14-18H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	167	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50210246 (1-(bis(2-chlorophenyl)methyl)-4-(2-((methylamino)m...) Show SMILES CNCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl Show InChI InChI=1S/C26H28Cl2N2O/c1-29-18-19-8-2-5-11-22(19)26(31)14-16-30(17-15-26)25(20-9-3-6-12-23(20)27)21-10-4-7-13-24(21)28/h2-13,25,29,31H,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	255	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50210246 (1-(bis(2-chlorophenyl)methyl)-4-(2-((methylamino)m...) Show SMILES CNCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl Show InChI InChI=1S/C26H28Cl2N2O/c1-29-18-19-8-2-5-11-22(19)26(31)14-16-30(17-15-26)25(20-9-3-6-12-23(20)27)21-10-4-7-13-24(21)28/h2-13,25,29,31H,14-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 3028-33 (2007) Article DOI: 10.1016/j.bmcl.2007.03.062 BindingDB Entry DOI: 10.7270/Q2Z31ZBS
					More data for this Ligand-Target Pair