BDBM50210351 CHEMBL3916448

SMILES: Oc1c(Br)cccc1C(=O)Nc1nc2ccc(Br)cc2s1

InChI Key: InChIKey=WBTGPBXPYXTKLB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50210351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pyruvate kinase (Staphylococcus aureus (strain MRSA252))	BDBM50210351 (CHEMBL3916448) Show SMILES Oc1c(Br)cccc1C(=O)Nc1nc2ccc(Br)cc2s1 Show InChI InChI=1S/C14H8Br2N2O2S/c15-7-4-5-10-11(6-7)21-14(17-10)18-13(20)8-2-1-3-9(16)12(8)19/h1-6,19H,(H,17,18,20)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Simon Fraser University Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal His-tagged methicillin-resistant Staphylococcus aureus MRSA252 pyruvate kinase expressed in Escherichia coli BL2...				Eur J Med Chem 125: 1-13 (2017) Article DOI: 10.1016/j.ejmech.2016.09.018 BindingDB Entry DOI: 10.7270/Q2CC12P0
					More data for this Ligand-Target Pair