BDBM50210375 1-(bis(2-chlorophenyl)methyl)-4-phenylpiperidin-4-ol::CHEMBL228911

SMILES: OC1(CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl)c1ccccc1

InChI Key: InChIKey=VYRHTEGFBOSTMB-UHFFFAOYSA-N

Data: 4 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50210375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50210375 (1-(bis(2-chlorophenyl)methyl)-4-phenylpiperidin-4-...) Show SMILES OC1(CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl)c1ccccc1 Show InChI InChI=1S/C24H23Cl2NO/c25-21-12-6-4-10-19(21)23(20-11-5-7-13-22(20)26)27-16-14-24(28,15-17-27)18-8-2-1-3-9-18/h1-13,23,28H,14-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210375 (1-(bis(2-chlorophenyl)methyl)-4-phenylpiperidin-4-...) Show SMILES OC1(CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl)c1ccccc1 Show InChI InChI=1S/C24H23Cl2NO/c25-21-12-6-4-10-19(21)23(20-11-5-7-13-22(20)26)27-16-14-24(28,15-17-27)18-8-2-1-3-9-18/h1-13,23,28H,14-17H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	256	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50210375 (1-(bis(2-chlorophenyl)methyl)-4-phenylpiperidin-4-...) Show SMILES OC1(CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl)c1ccccc1 Show InChI InChI=1S/C24H23Cl2NO/c25-21-12-6-4-10-19(21)23(20-11-5-7-13-22(20)26)27-16-14-24(28,15-17-27)18-8-2-1-3-9-18/h1-13,23,28H,14-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	635	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50210375 (1-(bis(2-chlorophenyl)methyl)-4-phenylpiperidin-4-...) Show SMILES OC1(CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl)c1ccccc1 Show InChI InChI=1S/C24H23Cl2NO/c25-21-12-6-4-10-19(21)23(20-11-5-7-13-22(20)26)27-16-14-24(28,15-17-27)18-8-2-1-3-9-18/h1-13,23,28H,14-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50210375 (1-(bis(2-chlorophenyl)methyl)-4-phenylpiperidin-4-...) Show SMILES OC1(CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl)c1ccccc1 Show InChI InChI=1S/C24H23Cl2NO/c25-21-12-6-4-10-19(21)23(20-11-5-7-13-22(20)26)27-16-14-24(28,15-17-27)18-8-2-1-3-9-18/h1-13,23,28H,14-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	222	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair