null

SMILES: OC1(CCN(CC1)C(c1cccs1)c1ccccc1)c1ccccc1

InChI Key: InChIKey=AEUSAZUUXLNHOA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210399   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50210399 (4-phenyl-1-(phenyl(thiophen-2-yl)methyl)piperidin-...) Show SMILES OC1(CCN(CC1)C(c1cccs1)c1ccccc1)c1ccccc1 |w:7.7| Show InChI InChI=1S/C22H23NOS/c24-22(19-10-5-2-6-11-19)13-15-23(16-14-22)21(20-12-7-17-25-20)18-8-3-1-4-9-18/h1-12,17,21,24H,13-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210399 (4-phenyl-1-(phenyl(thiophen-2-yl)methyl)piperidin-...) Show SMILES OC1(CCN(CC1)C(c1cccs1)c1ccccc1)c1ccccc1 |w:7.7| Show InChI InChI=1S/C22H23NOS/c24-22(19-10-5-2-6-11-19)13-15-23(16-14-22)21(20-12-7-17-25-20)18-8-3-1-4-9-18/h1-12,17,21,24H,13-16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	405	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50210399 (4-phenyl-1-(phenyl(thiophen-2-yl)methyl)piperidin-...) Show SMILES OC1(CCN(CC1)C(c1cccs1)c1ccccc1)c1ccccc1 |w:7.7| Show InChI InChI=1S/C22H23NOS/c24-22(19-10-5-2-6-11-19)13-15-23(16-14-22)21(20-12-7-17-25-20)18-8-3-1-4-9-18/h1-12,17,21,24H,13-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	971	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50210399 (4-phenyl-1-(phenyl(thiophen-2-yl)methyl)piperidin-...) Show SMILES OC1(CCN(CC1)C(c1cccs1)c1ccccc1)c1ccccc1 |w:7.7| Show InChI InChI=1S/C22H23NOS/c24-22(19-10-5-2-6-11-19)13-15-23(16-14-22)21(20-12-7-17-25-20)18-8-3-1-4-9-18/h1-12,17,21,24H,13-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair