BDBM50210400 1-((2-ethylphenyl)(phenyl)methyl)-4-phenylpiperidin-4-ol::CHEMBL228848

SMILES: CCc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1

InChI Key: InChIKey=KGIQHUIJGWLRHH-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50210400 (1-((2-ethylphenyl)(phenyl)methyl)-4-phenylpiperidi...) Show SMILES CCc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:8.9| Show InChI InChI=1S/C26H29NO/c1-2-21-11-9-10-16-24(21)25(22-12-5-3-6-13-22)27-19-17-26(28,18-20-27)23-14-7-4-8-15-23/h3-16,25,28H,2,17-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210400 (1-((2-ethylphenyl)(phenyl)methyl)-4-phenylpiperidi...) Show SMILES CCc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:8.9| Show InChI InChI=1S/C26H29NO/c1-2-21-11-9-10-16-24(21)25(22-12-5-3-6-13-22)27-19-17-26(28,18-20-27)23-14-7-4-8-15-23/h3-16,25,28H,2,17-20H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50210400 (1-((2-ethylphenyl)(phenyl)methyl)-4-phenylpiperidi...) Show SMILES CCc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:8.9| Show InChI InChI=1S/C26H29NO/c1-2-21-11-9-10-16-24(21)25(22-12-5-3-6-13-22)27-19-17-26(28,18-20-27)23-14-7-4-8-15-23/h3-16,25,28H,2,17-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	237	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50210400 (1-((2-ethylphenyl)(phenyl)methyl)-4-phenylpiperidi...) Show SMILES CCc1ccccc1C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1 |w:8.9| Show InChI InChI=1S/C26H29NO/c1-2-21-11-9-10-16-24(21)25(22-12-5-3-6-13-22)27-19-17-26(28,18-20-27)23-14-7-4-8-15-23/h3-16,25,28H,2,17-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	535	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair