null

SMILES: OC1(CCN(CC1)C(c1ccccc1)c1cccnc1)c1ccccc1

InChI Key: InChIKey=MEUYOYHIZBZUGT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50210417 (4-phenyl-1-(phenyl(pyridin-3-yl)methyl)piperidin-4...) Show SMILES OC1(CCN(CC1)C(c1ccccc1)c1cccnc1)c1ccccc1 |w:7.7| Show InChI InChI=1S/C23H24N2O/c26-23(21-11-5-2-6-12-21)13-16-25(17-14-23)22(19-8-3-1-4-9-19)20-10-7-15-24-18-20/h1-12,15,18,22,26H,13-14,16-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	323	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50210417 (4-phenyl-1-(phenyl(pyridin-3-yl)methyl)piperidin-4...) Show SMILES OC1(CCN(CC1)C(c1ccccc1)c1cccnc1)c1ccccc1 |w:7.7| Show InChI InChI=1S/C23H24N2O/c26-23(21-11-5-2-6-12-21)13-16-25(17-14-23)22(19-8-3-1-4-9-19)20-10-7-15-24-18-20/h1-12,15,18,22,26H,13-14,16-17H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	819	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50210417 (4-phenyl-1-(phenyl(pyridin-3-yl)methyl)piperidin-4...) Show SMILES OC1(CCN(CC1)C(c1ccccc1)c1cccnc1)c1ccccc1 |w:7.7| Show InChI InChI=1S/C23H24N2O/c26-23(21-11-5-2-6-12-21)13-16-25(17-14-23)22(19-8-3-1-4-9-19)20-10-7-15-24-18-20/h1-12,15,18,22,26H,13-14,16-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.99E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50210417 (4-phenyl-1-(phenyl(pyridin-3-yl)methyl)piperidin-4...) Show SMILES OC1(CCN(CC1)C(c1ccccc1)c1cccnc1)c1ccccc1 |w:7.7| Show InChI InChI=1S/C23H24N2O/c26-23(21-11-5-2-6-12-21)13-16-25(17-14-23)22(19-8-3-1-4-9-19)20-10-7-15-24-18-20/h1-12,15,18,22,26H,13-14,16-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 3023-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.061 BindingDB Entry DOI: 10.7270/Q24B3242
					More data for this Ligand-Target Pair