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SMILES: CN(C[C@@H](O)c1ccccc1)Cc1cc2c(s1)n(C)cc(C(=O)NCc1ccc(Cl)cc1)c2=O

InChI Key: InChIKey=ROOZBWRQVMVZNG-HSZRJFAPSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50210617   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA polymerase catalytic subunit


(Human cytomegalovirus (HCMV strain AD169) )		BDBM50210617
PNG
((S)-N-(4-chlorobenzyl)-2-(((2-hydroxy-2-phenylethy...)
Show SMILES CN(C[C@@H](O)c1ccccc1)Cc1cc2c(s1)n(C)cc(C(=O)NCc1ccc(Cl)cc1)c2=O
Show InChI InChI=1S/C26H26ClN3O3S/c1-29(16-23(31)18-6-4-3-5-7-18)14-20-12-21-24(32)22(15-30(2)26(21)34-20)25(33)28-13-17-8-10-19(27)11-9-17/h3-12,15,23,31H,13-14,16H2,1-2H3,(H,28,33)/t23-/m1/s1
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n/an/a 100n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of HCMV DNA polymerase by scintillation proximity assay

Bioorg Med Chem Lett 17: 3349-53 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.102
BindingDB Entry DOI: 10.7270/Q2HX1DHN
More data for this
Ligand-Target Pair