BindingDB logo
myBDB logout

null

SMILES: CCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN(C)CC(C)c3ccco3)sc12

InChI Key: InChIKey=OHECYBQYNPYFOO-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50210619   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA polymerase catalytic subunit


(Human cytomegalovirus (HCMV strain AD169) )		BDBM50210619
PNG
(CHEMBL394970 | N-(4-chlorobenzyl)-7-ethyl-2-(((2-(...)
Show SMILES CCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN(C)CC(C)c3ccco3)sc12 |w:25.26|
Show InChI InChI=1S/C26H28ClN3O3S/c1-4-30-16-22(25(32)28-13-18-7-9-19(27)10-8-18)24(31)21-12-20(34-26(21)30)15-29(3)14-17(2)23-6-5-11-33-23/h5-12,16-17H,4,13-15H2,1-3H3,(H,28,32)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 200n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of HCMV DNA polymerase by scintillation proximity assay

Bioorg Med Chem Lett 17: 3349-53 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.102
BindingDB Entry DOI: 10.7270/Q2HX1DHN
More data for this
Ligand-Target Pair