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Enter Data

null

SMILES: C[C@H]1CN(CCN1CC[C@@H]1OCCc2cc(ccc12)C(N)=O)c1ccc2cc(F)ccc2c1

InChI Key: InChIKey=RRWISUYOSRHAFZ-QYBDOPJKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50210641
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50210641 ((S)-1-(2-((S)-4-(6-fluoronaphthalen-2-yl)-2-methyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly SA Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human 5HT transpoter expressed in HEK293 cells				Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3
Lilly SA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50210641 ((S)-1-(2-((S)-4-(6-fluoronaphthalen-2-yl)-2-methyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly SA Curated by ChEMBL					Assay Description Displacement of [3H]GR125743 from human 5HT1D expressed in LM(tk-) cells				Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3
Lilly SA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50210641 ((S)-1-(2-((S)-4-(6-fluoronaphthalen-2-yl)-2-methyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	307	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly SA Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A expressed in LM(tk-) cells				Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3
Lilly SA Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50210641 ((S)-1-(2-((S)-4-(6-fluoronaphthalen-2-yl)-2-methyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly SA Curated by ChEMBL					Assay Description Displacement of [3H]GR125743 from human 5HT1B expressed in LM(tk-) cells				Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3
Lilly SA Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50210641 ((S)-1-(2-((S)-4-(6-fluoronaphthalen-2-yl)-2-methyl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly SA Curated by ChEMBL					Assay Description Displacement of [3H]raclopride from dopamine D2 receptor in rat caudate membranes				Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3
Lilly SA Curated by ChEMBL					More data for this Ligand-Target Pair