Found 4 hits for monomerid = 50210655 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210655
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)cc(F)c1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-9-3-8(14(19)11(18)5-9)4-10(23)6-13(28)26-1-2-27-12(7-26)24-25-15(27)16(20,21)22/h3,5,10H,1-2,4,6-7,23H2/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 805 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210655
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)cc(F)c1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-9-3-8(14(19)11(18)5-9)4-10(23)6-13(28)26-1-2-27-12(7-26)24-25-15(27)16(20,21)22/h3,5,10H,1-2,4,6-7,23H2/t10-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 805 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP4 (unknown origin) |
J Med Chem 51: 4359-69 (2008)
Article DOI: 10.1021/jm800219f BindingDB Entry DOI: 10.7270/Q28915N5 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase VIII
(Homo sapiens (Human)) | BDBM50210655
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)cc(F)c1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-9-3-8(14(19)11(18)5-9)4-10(23)6-13(28)26-1-2-27-12(7-26)24-25-15(27)16(20,21)22/h3,5,10H,1-2,4,6-7,23H2/t10-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210655
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)cc(F)c1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-9-3-8(14(19)11(18)5-9)4-10(23)6-13(28)26-1-2-27-12(7-26)24-25-15(27)16(20,21)22/h3,5,10H,1-2,4,6-7,23H2/t10-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098 BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this Ligand-Target Pair | |