BDBM50210704 CHEMBL3948354

SMILES: COc1cc2c(Nc3ccc(NC(=O)Nc4ccccc4)c(Cl)c3)ncnc2cc1OCCN1CCCCC1

InChI Key: InChIKey=XHCOFOGGHUGORL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50210704 (CHEMBL3948354) Show SMILES COc1cc2c(Nc3ccc(NC(=O)Nc4ccccc4)c(Cl)c3)ncnc2cc1OCCN1CCCCC1 Show InChI InChI=1S/C29H31ClN6O3/c1-38-26-17-22-25(18-27(26)39-15-14-36-12-6-3-7-13-36)31-19-32-28(22)33-21-10-11-24(23(30)16-21)35-29(37)34-20-8-4-2-5-9-20/h2,4-5,8-11,16-19H,3,6-7,12-15H2,1H3,(H,31,32,33)(H2,34,35,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human VEGFR-2 cytoplasmic domain (790 to 1356 residues) expressed in baculovirus expression system preincubated f...				Eur J Med Chem 125: 245-254 (2017) Article DOI: 10.1016/j.ejmech.2016.09.039 BindingDB Entry DOI: 10.7270/Q2QJ7K9C
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50210704 (CHEMBL3948354) Show SMILES COc1cc2c(Nc3ccc(NC(=O)Nc4ccccc4)c(Cl)c3)ncnc2cc1OCCN1CCCCC1 Show InChI InChI=1S/C29H31ClN6O3/c1-38-26-17-22-25(18-27(26)39-15-14-36-12-6-3-7-13-36)31-19-32-28(22)33-21-10-11-24(23(30)16-21)35-29(37)34-20-8-4-2-5-9-20/h2,4-5,8-11,16-19H,3,6-7,12-15H2,1H3,(H,31,32,33)(H2,34,35,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	212	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system preincubated for ...				Eur J Med Chem 125: 245-254 (2017) Article DOI: 10.1016/j.ejmech.2016.09.039 BindingDB Entry DOI: 10.7270/Q2QJ7K9C
					More data for this Ligand-Target Pair