BDBM50210884 1-(1-(3-methoxy-4-methylbenzoyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::CHEMBL251402
SMILES: COc1cc(ccc1C)C(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O
InChI Key: InChIKey=WMRDDSTTZQYJLV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50210884 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human)) | BDBM50210884
(1-(1-(3-methoxy-4-methylbenzoyl)piperidin-4-yl)-1H...)Show SMILES COc1cc(ccc1C)C(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C21H23N3O3/c1-14-7-8-15(13-19(14)27-2)20(25)23-11-9-16(10-12-23)24-18-6-4-3-5-17(18)22-21(24)26/h3-8,13,16H,9-12H2,1-2H3,(H,22,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description
Inhibition of human 11betaHSD1 by SPA |
Bioorg Med Chem Lett 17: 3421-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.083
BindingDB Entry DOI: 10.7270/Q2GX4B72 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase 2
(Homo sapiens (Human)) | BDBM50210884
(1-(1-(3-methoxy-4-methylbenzoyl)piperidin-4-yl)-1H...)Show SMILES COc1cc(ccc1C)C(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O Show InChI InChI=1S/C21H23N3O3/c1-14-7-8-15(13-19(14)27-2)20(25)23-11-9-16(10-12-23)24-18-6-4-3-5-17(18)22-21(24)26/h3-8,13,16H,9-12H2,1-2H3,(H,22,26) | KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum AB
Curated by ChEMBL
| Assay Description
Inhibition of 11betaHSD2 |
Bioorg Med Chem Lett 17: 3421-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.083
BindingDB Entry DOI: 10.7270/Q2GX4B72 |
More data for this
Ligand-Target Pair | |
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