BDBM50211144 (R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)-N-(2-(1-methyl-1H-imidazol-4-yl)-2-oxoethyl)-2-(4-(trifluoromethyl)phenyl)acetamide::CHEMBL397675

SMILES: C[C@@H](N(CC(=O)c1cn(C)cn1)C(=O)Cc1ccc(cc1)C(F)(F)F)c1nc2ccccc2c(=O)n1-c1ccc(F)cc1

InChI Key: InChIKey=HBCOZZLXDKBWKL-LJQANCHMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50211144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human))	BDBM50211144 ((R)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquin...) Show SMILES C[C@@H](N(CC(=O)c1cn(C)cn1)C(=O)Cc1ccc(cc1)C(F)(F)F)c1nc2ccccc2c(=O)n1-c1ccc(F)cc1 Show InChI InChI=1S/C31H25F4N5O3/c1-19(29-37-25-6-4-3-5-24(25)30(43)40(29)23-13-11-22(32)12-14-23)39(17-27(41)26-16-38(2)18-36-26)28(42)15-20-7-9-21(10-8-20)31(33,34)35/h3-14,16,18-19H,15,17H2,1-2H3/t19-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMC				Bioorg Med Chem Lett 17: 3339-43 (2007) Article DOI: 10.1016/j.bmcl.2007.03.106 BindingDB Entry DOI: 10.7270/Q2VT1SXN
					More data for this Ligand-Target Pair