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BDBM50211153 (R)-N-(2-(1H-imidazol-4-yl)-2-oxoethyl)-N-(1-(3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)-2-(4-(trifluoromethyl)phenyl)acetamide::CHEMBL231485

SMILES: C[C@@H](N(CC(=O)c1cnc[nH]1)C(=O)Cc1ccc(cc1)C(F)(F)F)c1nc2ccccc2c(=O)n1-c1ccc(F)cc1

InChI Key: InChIKey=DJQFCUMDGZOVRV-GOSISDBHSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50211153   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
chemokine (C-X-C motif) receptor 3


(Homo sapiens (Human))		BDBM50211153
PNG
((R)-N-(2-(1H-imidazol-4-yl)-2-oxoethyl)-N-(1-(3-(4...)
Show SMILES C[C@@H](N(CC(=O)c1cnc[nH]1)C(=O)Cc1ccc(cc1)C(F)(F)F)c1nc2ccccc2c(=O)n1-c1ccc(F)cc1
Show InChI InChI=1S/C30H23F4N5O3/c1-18(28-37-24-5-3-2-4-23(24)29(42)39(28)22-12-10-21(31)11-13-22)38(16-26(40)25-15-35-17-36-25)27(41)14-19-6-8-20(9-7-19)30(32,33)34/h2-13,15,17-18H,14,16H2,1H3,(H,35,36)/t18-/m1/s1
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n/an/a 650n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I ]IP10 from CXCR3 receptor expressed in PBMC

Bioorg Med Chem Lett 17: 3339-43 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.106
BindingDB Entry DOI: 10.7270/Q2VT1SXN
More data for this
Ligand-Target Pair